| 摘要 |
It is intended to provide a compound represented by the following general formula or its salt: wherein R1 represents C1-4 alkyl; R2 represents (1) a nitrogen-containing 5- to 7-membered heterocyclic group optionally having a substituent selected from among (1aCOE) halogeno, (2aCOE) hydroxy, (3aCOE) C1-4 alkyl and (4aCOE) C1-4 alkoxy, (2) phenyl optionally having a substituent selected from among (1aCOE) halogeno, (2aCOE) C1-4 alkoxy-C1-4 alkyl, (3aCOE) mono C1-4 alkyl-carbamoyl-C1-4 alkyl, (4aCOE) C1-4 alkoxy and (5aCOE) mono C1-4 alkylcarbamoyl-C1-4 alkoxy, etc.; R3 represents C1-4 alkyl; R4 represents C1-4 alkoxy, etc.; and n is an integer of from 1 to 4; as a thienopyrimidine compound having antagonism to gonadotropin-releasing hormone. |
