发明名称 |
Protease conjugates having sterically protected epitope regions |
摘要 |
The present disclosure relates to subtilisin protease conjugate comprising a protease moiety and one or more addition moieties. Each addition moiety is covalently attached to an epitope protection position of the protease moiety. The protease conjugates have decreased immunogenicity relative to a parent protease. The present disclosure further relates to cleaning and personal care compositions comprising the protease conjugates.
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申请公布号 |
US6946128(B1) |
申请公布日期 |
2005.09.20 |
申请号 |
US20000618235 |
申请日期 |
2000.07.18 |
申请人 |
THE PROCTER & GAMBLE COMPANY |
发明人 |
RUBINGH DONN NELTON;WEISGERBER DAVID JOHN;CORREA PAUL ELLIOTT |
分类号 |
A61K38/48;C12N9/52;C12N9/54;C12N9/96;C12S9/00;C12S11/00;(IPC1-7):A61K38/48 |
主分类号 |
A61K38/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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