| 发明名称 |
Benzimidazole quinolinones and uses thereof |
| 摘要 |
Methods of treating cancer include contacting a cancer cell with 4-amino-5-fluoro-3-(5-piperazin-1-yl-1H-benzimidazol-2-yl)quinolin-2(1H)-one, 4-amino-5-fluoro-3-[5-(4-methyl-4-oxidopiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one, tautomers thereof, pharmaceutically acceptable salts thereof, pharmaceutically acceptable salts of the tautomers thereof, or a mixture thereof.
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| 申请公布号 |
US2005203101(A1) |
申请公布日期 |
2005.09.15 |
| 申请号 |
US20040839793 |
申请日期 |
2004.05.05 |
| 申请人 |
CHIRON CORPORATION |
发明人 |
BARSANTI PAUL A.;BUSSIERE DIRKSEN;HARRISON STEPHEN D.;HEISE CARLA C.;JANSEN JOHANNA M.;JAZAN ELISA;MACHAJEWSKI TIMOTHY D.;MCBRIDE CHRISTOPHER;MCCREA WILLIAM R.JR.;NG SIMON;NI ZHI-JIE;PECCHI SABINA;PFISTER KEITH B.;RAMURTHY SAVITHRI;RENHOWE PAUL A.;SHAFER CYNTHIA M.;SILVER JOEL B.;WAGMAN ALLAN S.;WIESMANN MARION;WAYMAN KELLY |
| 分类号 |
A61K31/4375;A61K31/4709;A61K31/496;A61K31/52;A61P35/00;C07D401/04;C07D401/14;C07D405/14;C07D409/14;C07D413/14;C07D453/02;C07D453/06;C07D471/04;(IPC1-7):A61K31/496;C07D43/14 |
主分类号 |
A61K31/4375 |
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