The present invention relates to a chimeric pRNA monomer that is selected from: (a) a chimeric pRNA monomer comprising a siRNA; (b) a chimeric pRNA monomer comprising a biologically active moiety at at least one of the 5' or the 3' end; and (c) a chimeric pRNA monomer comprising a 3' end annealed to an oligonucleotide.
申请公布号
EP1573070(A2)
申请公布日期
2005.09.14
申请号
EP20030816665
申请日期
2003.12.16
申请人
PURDUE RESEARCH FOUNDATION;GUO, PEIXUAN;HOEPRICH, STEPHEN M.;SHU, DAN