RECOMBINANT INTRACELLULAR PATHOGEN IMMUNOGENIC COMPOSITIONS AND METHODS FOR USE
摘要
Immunogenic compositions comprising recombinant attenuated intracellular pathogens that have been transformed to express recombinant immunogenic antigens of the same or other intracellular pathogens are provided. Exemplary immunogenic compositions include, but are not limited to attenuated recombinant Mycobacteria expressing the major extracellular non-fusion proteins of Mycobacteria and/or other intracellular pathogens. Other embodiments are provided wherein the recombinant attenuated intracellular pathogen is auxotrophic.
申请公布号
WO2005037222(A3)
申请公布日期
2005.09.09
申请号
WO2004US34206
申请日期
2004.10.15
申请人
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;HORWITZ, MARCUS, A.;HARTH, GUNTER;TULLIUS, MICHAEL, V.
发明人
HORWITZ, MARCUS, A.;HARTH, GUNTER;TULLIUS, MICHAEL, V.