METHODS FOR SCREENING INSECTICIDES

摘要

The present invention relates to methods of screening for potential insecticidal agents using genes encoding proteins that regulate xenobiotic detoxification in insects. In particular the invention relates to methods of using insect nuclear hormone receptor genes, in particular dhr96 or homologues thereof and/or their promoters. Such methods employ inter alia transgenic cells and/or transgenic whole organisms in which one or more nuclear hormone receptor gene is deleted or under-expressed.