| 发明名称 |
2-(PYRIDIN-3-YLAMINO)-PYRIDO[2,3-D]PYRIMIDIN-7-ONES |
| 摘要 |
<p>This invention provides compounds of formula I:R<1 >wherein R', R<2>, R<3>, R<4>, and X<1> are as defined in the specification. The 2-(pyridin-3-ylamino)-pyrido[2,3-d]pyrimidin-7-one compounds of formula I, which are inhibitors of cyclin-dependent kinases 2 and 4 (Cdk2 and Cdk4), are useful in treating cell proliferative disorders.</p> |
| 申请公布号 |
WO2005082903(A1) |
申请公布日期 |
2005.09.09 |
| 申请号 |
WO2005IB00300 |
申请日期 |
2005.02.07 |
| 申请人 |
WARNER-LAMBERT COMPANY LLC;BARVIAN, MARK, ROBERT;TOOGOOD, PETER, LAURENCE;VANDERWEL, SCOTT, NORMAN |
发明人 |
BARVIAN, MARK, ROBERT;TOOGOOD, PETER, LAURENCE;VANDERWEL, SCOTT, NORMAN |
| 分类号 |
A61K31/519;C07D213/74;C07D471/04;C07D487/02;(IPC1-7):C07D471/04;A61K31/505;A61P35/00 |
主分类号 |
A61K31/519 |
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