发明名称 METHOD FOR THE PRODUCTION OF HYPERBRANCHED POLYSACCHARIDE FRACTIONS
摘要 The invention relates to a method for producing hyperbranched amylopectin having a mean molecular weight ranging between 2,000 and 29,000 Dalton and a n average degree of branching of more than 10 percent and less than 20 percent , said degree of branching being expressed in mole percent of the anhydrogluco se units carrying branching points. According to the inventive method, the molecular weight of plant amylopectins or starch rich in amylopectin is reduced to molecular weights not exceeding 60,000 Dalton by means of a-amyla se or acid hydrolysis in a first hydrolysis step, and the molecular weight of t he reduced product obtained in the first hydrolysis step is further reduced by means of .szlig.-amylase reduction in a second hydrolysis step. The inventio n further relates to the production of coupling products of the hyperbranched amylopectin with a pharmaceutical agent.
申请公布号 CA2556114(A1) 申请公布日期 2005.09.09
申请号 CA20052556114 申请日期 2005.02.26
申请人 FRESENIUS KABI DEUTSCHLAND GMBH 发明人 SOMMERMEYER, KLAUS
分类号 C12P19/22;A61K31/718;A61K47/48;C08B30/12;C08B30/18;C08B30/20;C08B35/00;C08B35/08;C12P19/14 主分类号 C12P19/22
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