| 摘要 |
<p>A pharmaceutical composition of small sized unilamellar liposomes for the supply active principles by injection, with an improved permanency in the blood flow, where the unilamellar membrane contains a mixture of saturated lipids encompassing at least one lysophospholipid in a quantity from about 0.5 mol% to about 6,0 mol % with reference total lipids and the production method. Additionally, liposomes of high encapsulation efficiency of an active principle like doxorubicine are prepared through the adding of a solution of calcium ions.</p> |
