P53 WILD-TYPE AS BIOMARKER FOR THE TREATMENT WITH MTOR INHIBITORS IN COMBINATION WITH A CYTOTOXIC AGENT
摘要
Provided are biomarkers for determining the sensitivity of proliferative diseases such as cancer to therapeutic agents, in particular mTOR inhibitors in combination with a cytotoxic agent, in particular a cytotoxic agent which damages or affects the integrity of DNA.
申请公布号
WO2005080593(A2)
申请公布日期
2005.09.01
申请号
WO2005EP01849
申请日期
2005.02.22
申请人
NOVARTIS AG;NOVARTIS PHARMA GMBH;NOVARTIS FORSCHUNGSSTIFTUNG;BEUVINK, IWAN;BOULAY, ANNE;LANE, HEIDI;O'REILLY, TERENCE;THOMAS, GEORGE
发明人
BEUVINK, IWAN;BOULAY, ANNE;LANE, HEIDI;O'REILLY, TERENCE;THOMAS, GEORGE
