PROCESS FOR ENCAPSULATING SHEAR SENSITIVE FILL MASSES INTO CAPSULES AND CAPSULES CONTAINING SHEAR SENSITIVE FILL MASSES

摘要

THE PRESENT INVENTION PROVIDES A PROCESS FOR ENCAPSULATING A SHEAR SENSITIVE FILL MASS WHICH CONTAINS A PHARMACEUTICAL ACTIVE AGENT OR NUTRIENT, CHARACTERIZED IN THAT SAID FILL MASS IS HEATED AND SUBSEQUENTLY COOLED, PRIOR TO THE ENCAPSULATION. THE INVENTION ALSO PROVIDES CAPSULES COMPRISING SHEAR SENSITIVE FILL MATERIAL OBTAINED BY THE SAID PROCESS WHICH HAVE A HIGH AND CONSTANT DISSOLUTION RATE.