SUGAR-CHAIN ASPARAGINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF

摘要

Sugar-chain asparagine derivatives having undeca- to tri-saccharides as represented by the general formula (1): (1) [wherein R1 and R2 are each independently hydrogen or a group represented by one of the general formulae (2) to (6) set forth in the description; and Q is a biotinyl group or an FITC group]; sugar-chain asparagine derivatives wherein the amino nitrogen of asparagine is modified with a biotinyl group or an FITC group and at least one fucose molecule is bonded to the N-acetyl- glucosamine on the nonreducing end side; microplates to which biotinylated sugar-chain asparagines are bonded; and affinity columns to which biotinylated sugar- chain asparagines are bonded.