发明名称 4-amino-6-phenyl-pyrrolo[2,3-d]pyrimidine derivatives
摘要 Disclosed are compounds of the formula (I); wherein R1 and R2 are each independently of the other hydrogen, unsubstituted or substituted alkyl or cycloalkyl, a heterocyclic radical bonded via a ring carbon atom, or a radical of the formula R4-Y-(C=Z)- wherein R4 is unsubstituted, mono- or disubstituted amino or a heterocyclic radical, Y is either not present or lower alkyl and Z is oxygen, sulfur or imino, with the proviso that R1 and R2 are not both hydrogen; or R1 and R2 together with the nitrogen atom to which they are attached form a heterocyclic radical; R3 is a heterocyclic radical or an unsubstituted or substituted aromatic radical; G is C1-C7-alkylene, -C(=O)-, or C1-C6-alkylene wherein the carbonyl group is attached to the NR1R2 moiety; Q is -NH- or -O-, with the proviso that Q is -O- if G is -C(=O)- or C1-C6-alkylene-C(=O)-; and X is either not present or C1-C7alkylene, with the proviso that a heterocyclic radical R3 is bonded via a ring carbon atom if X is not present; or a salt thereof. Further disclosed is a process for the production of compounds of the formula (I) and the use of those compounds or their salts in the manufacture of a medicament.
申请公布号 NZ530824(A) 申请公布日期 2005.08.26
申请号 NZ20020530824 申请日期 2002.08.06
申请人 NOVARTIS AG 发明人 BOLD, GUIDO;CAPRARO, HANS-GEORG;CARAVATTI, GIORGIO;TRAXLER, PETER
分类号 A61K31/519;A61K31/5377;A61P35/00;A61P43/00;C07D487/04;(IPC1-7):A61K31/519 主分类号 A61K31/519
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