| 发明名称 |
Inhibitors of akt activity |
| 摘要 |
The present invention is directed to compounds comprising a 2,3-diphenylpyrazine moiety which inhibit the activity of Akt, a serine/threonine protein kinase. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for treating cancer comprising administration of the compounds of the invention.
|
| 申请公布号 |
US2005182256(A1) |
申请公布日期 |
2005.08.18 |
| 申请号 |
US20040509959 |
申请日期 |
2004.10.04 |
| 申请人 |
DUGGAN MARK E.;LINDSLEY CRAIG W.;ZHAO ZHIJIAN |
发明人 |
DUGGAN MARK E.;LINDSLEY CRAIG W.;ZHAO ZHIJIAN |
| 分类号 |
A61K31/497;A61K45/00;A61P35/00;A61P43/00;C07D241/18;C07D401/14;(IPC1-7):A61K31/497;C07D43/02 |
主分类号 |
A61K31/497 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
