发明名称 |
Tetrahydroisoquinolinyl derivatives of quinazoline and isoquinoline |
摘要 |
The invention pertains to substituted quinazoline and isoquinoline compounds that serve as effective phosphodiesterase (PDE) inhibitors. In particular, the invention relates to said compounds which are selective inhibitors of PDE-10. The invention also relates to intermediates for preparation of said compounds; pharmaceutical compositions comprising said compounds; and the use of said compounds in a method for treating certain central nervous system (CNS) or other disorders.
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申请公布号 |
US2005182079(A1) |
申请公布日期 |
2005.08.18 |
申请号 |
US20050062133 |
申请日期 |
2005.02.18 |
申请人 |
PFIZER INC |
发明人 |
ALLEN MARTIN P.;CHAPPIE THOMAS A.;HUMPHREY JOHN M.;LIRAS SPIROS |
分类号 |
C07D401/04;C07D491/04;(IPC1-7):A61K31/517;C07D43/02 |
主分类号 |
C07D401/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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