发明名称 |
2-(3-SUBSTITUTED-ARYL)AMINO-4-ARYL-THIAZOLES AS TYROSINE KINASE INHIBITORS |
摘要 |
<p>The present invention relates to novel compounds selected from 2-(3substitutedaryl)amino-4-aryl-thiazoles that selectively modulate, regulate, and/or inhibit signal transduction mediated by certain native and/or mutant tyrosine kinases implicated in a variety of human and animal diseases such as cell proliferative, metabolic, allergic, and degenerative disorders. More particularly, these compounds are potent and selective c-kit inhibitors.</p> |
申请公布号 |
WO2005073225(A1) |
申请公布日期 |
2005.08.11 |
申请号 |
WO2005IB00401 |
申请日期 |
2005.01.28 |
申请人 |
AB SCIENCE;MOUSSY, ALAIN;CIUFOLINI, MARCO;WERMUTH, CAMILLE;GIELTHEN, BRUNO |
发明人 |
MOUSSY, ALAIN;CIUFOLINI, MARCO;WERMUTH, CAMILLE;GIELTHEN, BRUNO |
分类号 |
C07D417/04;C07D417/14;(IPC1-7):C07D417/04;A61K31/443 |
主分类号 |
C07D417/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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