发明名称 |
Iap binding peptides and assays for identifying compounds that bind iap |
摘要 |
Assays are disclosed for identifying peptides and peptidomimetics for promoting apotosis in cells, through a pathway involving the Inhibitor of Apoptosis Proteins (IAPs), exemplified by XIAP, and the mitochondrial protein Smac/DIABOLO (hereinafter Smac) and homologs thereof. Also disclosed are IAP-binding peptides and peptidomimetics identified through the use of the assay.
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申请公布号 |
US2005176649(A1) |
申请公布日期 |
2005.08.11 |
申请号 |
US20030478521 |
申请日期 |
2003.11.20 |
申请人 |
MCLENDON GEORGE;KIPP RACHEL A.;CASE MARTIN;SHI YIGONG |
发明人 |
MCLENDON GEORGE;KIPP RACHEL A.;CASE MARTIN;SHI YIGONG |
分类号 |
G01N33/566;A61K38/05;C07K5/06;C07K5/103;G01N21/78;G01N33/15;G01N33/50;G01N33/53;G01N33/533;G01N33/58;G01N33/68;(IPC1-7):A61K38/05 |
主分类号 |
G01N33/566 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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