发明名称 |
PRODRUGS BUILT AS MULTIPLE SELF-ELIMINATION-RELEASE SPACERS |
摘要 |
<p>This invention concerns multiple release spacers and spacer systems, which release multiple leaving groups following a single activation. It concerns compounds comprising a specifier linked to two or more of the same or different leaving groups (L in the figure) via a self-eliminating multiple release spacer or spacer system, which compounds upon a single activation step, in particular removal or transformation of the specifier, release at least two leaving groups.</p> |
申请公布号 |
EP1560599(A1) |
申请公布日期 |
2005.08.10 |
申请号 |
EP20030774383 |
申请日期 |
2003.11.14 |
申请人 |
SYNTARGA B.V. |
发明人 |
DE GROOT, FRANCISCUS, MARINUS, HENDRIKUS;BEUSKER, PATRICK, HENRY;SCHEEREN, JOHANNES, WILHELM |
分类号 |
A61K47/48;C07C271/28;(IPC1-7):A61K47/48 |
主分类号 |
A61K47/48 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|