| 发明名称 |
Naphathalene derivatives which bind to the EP4 receptor |
| 摘要 |
Compounds of formula (I) and pharmaceutically acceptable derivatives thereof bind with high affinity to the EP4 receptor and are of use in the treatment or prevention of conditions such as a pain, inflammatory, immunological, bone, neurodegenerative or renal disorder.
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| 申请公布号 |
US6924297(B2) |
申请公布日期 |
2005.08.02 |
| 申请号 |
US20040450891 |
申请日期 |
2004.01.30 |
| 申请人 |
SMITHKLINE BEECHAM CORPORATION |
发明人 |
GIBLIN GERARD MARTIN PAUL;JONES HAYDN TERENCE;MASON ANDREW MCMURTRIE;MILLER NEIL DEREK;ROOMANS SUSAN;SHANAHAN STEPHEN EDWARD;WALKER ANN LOUISE |
| 分类号 |
C07D401/12;A61K31/403;A61K31/42;A61K31/427;A61K31/4439;A61P1/00;A61P1/02;A61P1/04;A61P1/12;A61P1/16;A61P3/00;A61P3/02;A61P3/10;A61P3/14;A61P5/10;A61P5/18;A61P7/02;A61P7/06;A61P7/12;A61P9/00;A61P9/10;A61P11/00;A61P11/02;A61P11/06;A61P13/04;A61P13/12;A61P15/10;A61P17/00;A61P17/02;A61P17/04;A61P17/06;A61P19/02;A61P19/04;A61P19/06;A61P19/08;A61P19/10;A61P21/00;A61P21/04;A61P25/02;A61P25/06;A61P25/14;A61P25/16;A61P25/20;A61P25/28;A61P25/30;A61P25/32;A61P25/34;A61P25/36;A61P27/02;A61P27/06;A61P27/14;A61P29/00;A61P31/00;A61P31/12;A61P31/16;A61P31/18;A61P35/00;A61P37/06;A61P39/02;A61P43/00;C07D209/64;C07D209/66;C07D403/12;C07D405/12;C07D409/12;C07D413/12;C07D417/12;(IPC1-7):A61K31/403;C07D209/60 |
主分类号 |
C07D401/12 |
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