发明名称 |
Device and method of detecting mutations and polymorphisms in DNA |
摘要 |
There is provided a resonator sensor useful for detecting polymorphisms and mutations in DNA. The resonator sensor has a capture molecule immobilised on its surface, the capture molecule being either a probe DNA containing a reference sequence, or a mismatch binding molecule, and being capable of forming a probe DNA/target DNA/mismatch binding molecule complex on the surface of the resonator. A method for detecting mutations in a target DNA, including single nucleotide polymorphisms, is also provided.
|
申请公布号 |
US2005164236(A1) |
申请公布日期 |
2005.07.28 |
申请号 |
US20040948275 |
申请日期 |
2004.09.22 |
申请人 |
SU XIAODI;ROBELEK RUDOLF;KNOLL WOLFGANG;O'SHEA SEAN |
发明人 |
SU XIAODI;ROBELEK RUDOLF;KNOLL WOLFGANG;O'SHEA SEAN |
分类号 |
C12Q1/68;G01N33/48;G01N33/50;G01N33/543;G06F19/00;(IPC1-7):C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|