摘要 |
<P>PROBLEM TO BE SOLVED: To provide a metal-diamine complex using an optically active octahydrobisisoquinoline that is prepared by predominantly synthesizing racemic octahydrobisisoquinoline followed by optical resolution of the racemic isomer and provide the asymmetric coupling method using the complex. <P>SOLUTION: The metal-diamine complex is prepared from (+)- or (-)-octahydrobisisoquinoline and a metal compound. <P>COPYRIGHT: (C)2005,JPO&NCIPI |