发明名称 N-containing five-membered ring compounds and pharmaceutical agents comprising the same as active ingredient
摘要 An N-containing five-membered ring compound of formula (I) wherein all symbols are the same as described in the specification, and a non-toxic salt thereof. The compound of formula (I) has an inhibitory activity against cysteine protease and therefore it is useful as an agent for the prophylaxis and/or treatment of inflammatory diseases, diseases induced by apoptosis, diseases induced by disorders of immune responses, autoimmune diseases, diseases induced by decomposition of proteins which compose organism, shock, circulatory system disorders, blood coagulation systems disorders, malignant tumors, acquired immune deficiency syndrome (AIDS) and AIDS-related complex (ARC), parasitic diseases, nerve degeneration diseases, pulmonary disorders, bone resorption diseases, endocrinesthenia, etc.
申请公布号 US2005164954(A1) 申请公布日期 2005.07.28
申请号 US20040018465 申请日期 2004.12.22
申请人 ONO PHARMACEUTICAL CO., LTD. 发明人 OHMOTO KAZUYUKI;ITAGAKI IORI
分类号 A61K31/41;A61K31/4245;A61K31/4439;A61K31/454;A61K31/5377;C07D257/04;C07D257/06;C07D271/06;C07D271/07;C07D401/04;C07D401/06;C07D403/12;C07D413/04;C07D413/06;(IPC1-7):A61K38/04;C07K5/04 主分类号 A61K31/41
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