发明名称 A SEGMENT OF GLYCOSYLATION-DEFICIENT HGF ALPHA-CHAIN
摘要 The present invention provides a segment of glycosylation-deficient HGF having mutation(s) introduced into an amino acid sequence so as to prevent glycosylation at least one glycosylation site of a hepatocyte growth factor (HGF), and a method of producing the same. The segment of glycosylation-deficient HGF of the present invention has the same activity as that of a segment of glycosylated HGF, therefore, it is useful as an alternate for a segment of glycosylated HGF.
申请公布号 CA2494384(A1) 申请公布日期 2005.07.27
申请号 CA20052494384 申请日期 2005.01.25
申请人 NAKAMURA, TOSHIKAZU;KRINGLE PHARMA INC. 发明人 NAKAMURA, TOSHIKAZU;MATSUMOTO, KUNIO;FUKUTA, KAZUHIRO
分类号 A61K38/00;C07K14/475;(IPC1-7):C12N15/18;A61K31/708;A61K38/18;A61K48/00;C12P21/02 主分类号 A61K38/00
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