发明名称 |
Altering memory by affecting STAUFEN function |
摘要 |
The present invention provides methods for screening a pharmaceutical agent for its ability to modulate long term memory formation, performance of a hippocampal-dependent cognitive task or STAUFEN function. The present invention also provides methods for modulating long term memory formation or performance of a hippocampal-dependent cognitive task by modulating staufen-dependent protein expression. The present invention further provides methods for treating a defect in long term memory formation associated with a defect in STAUFEN and methods for treating a defect in performance of a hippocampal-dependent cognitive task associated with a defect in STAUFEN.
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申请公布号 |
US2005158243(A1) |
申请公布日期 |
2005.07.21 |
申请号 |
US20040020026 |
申请日期 |
2004.12.21 |
申请人 |
HELICON THERAPEUTICS, INC. |
发明人 |
TULLY TIMOTHY P.;SCOTT RODERICK E.;BOURTCHOULADZE RUSIKO |
分类号 |
G01N33/50;G01N33/68;(IPC1-7):A61K49/00;C12Q1/68;A61K48/00 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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