CRYSTAL FORM OF QUINOLINE COMPOUND AND PROCESS FOR ITS PRODUCTION
摘要
<p>A method for producing a drug substance of crystalline pitavastatin calcium excellent in stability, is presented. In the production of a compound (pitavastatin calcium) represented by the formula (1): The water content is adjusted to a level of from 5 to 15%, and the crystal form is controlled to be crystal form A, thereby to obtain a drug substance excellent in stability.</p>
申请公布号
WO2005063711(A1)
申请公布日期
2005.07.14
申请号
WO2004JP19451
申请日期
2004.12.17
申请人
NISSAN CHEMICAL INDUSTRIES, LTD.;OHARA, YOSHIO;TAKADA, YASUTAKA;MATSUMOTO, HIROO;YOSHIDA, AKIHIRO