METHOD FOR DETECTING ANALYTES BASED ON EVANESCENT ILLUMINATION AND SCATTER-BASED DETECTION OF NANOPARTICLE PROBE COMPLEXES
摘要
The invention provides methods of detecting one or more specific binding analytes, such as nucleic acids and proteins, in the presence of a neutral or anionic polysaccharide, through light scattering techniques, where a change in light scattering caused by the formation of nanoparticle label complexes within the penetration depth of the evanescent wave of a wave guide signals the presence of the analyte.
申请公布号
WO2005008222(A3)
申请公布日期
2005.07.14
申请号
WO2004US16656
申请日期
2004.05.27
申请人
NANOSPHERE, INC.;STORHOFF, JAMES, J.;LUCAS, ADAM;MUELLER, UWE, R.;BAO, YIJIA, P.
发明人
STORHOFF, JAMES, J.;LUCAS, ADAM;MUELLER, UWE, R.;BAO, YIJIA, P.