COMPOUNDS AND METHODS FOR DEVELOPMENT OF RET MODULATORS
摘要
<p>Compounds active on Ret are described, as well as methods of using such compounds. Also described are crystal structures of Ret surrogates that were determined using X-ray crystallography. The use of such Ret surrogate crysta ls and strucural information can, for example, be used for identifying molecula r scaffolds and for developing ligands that bind to and modulate Ret and for identifying improved ligands based on known ligands.</p>
