| 发明名称 |
STEROIDS HAVING A MIXED ANDROGENIC AND PROGESTAGENIC PROFILE |
| 摘要 |
This invention provides 19-nor-D-homosteroids, having a mixed androgenic/progestagenic profile, which are orally active, prevent trabecular bone mineral density (BMD) loss, and which lack liver toxicity, having a structure according to the formula (I) wherein, R<1> is O, or NOR, with R being hydrogen, (Cl-6)alkyl or (Cl-6)acyl, R<2> is methyl or ethyl, and R<3> is hydrogen or (C1-15)acyl. |
| 申请公布号 |
WO2005061528(A2) |
申请公布日期 |
2005.07.07 |
| 申请号 |
WO2004EP53475 |
申请日期 |
2004.12.15 |
| 申请人 |
AKZO NOBEL N.V.;VAN DER LOUW, JAAP;LEYSEN, DIRK;GROOTENHUIS, ARIJ, JAN;DE GOOIJER, MARCEL, EVERT |
发明人 |
VAN DER LOUW, JAAP;LEYSEN, DIRK;GROOTENHUIS, ARIJ, JAN;DE GOOIJER, MARCEL, EVERT |
| 分类号 |
C07J63/00 |
主分类号 |
C07J63/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
