摘要 |
PROBLEM TO BE SOLVED: To provide a method of manufacturing a sulfonic acid chloride with a good yield and operability from a sulfonic acid or its salt. SOLUTION: In this manufacturing method of a sulfonic acid chloride, it is manufactured by reacting a sulfonic acid or its salt with a chlorination agent such as phosgene, an oxyphosphorus chloride, a thionyl chloride, etc., in a solvent comprising an aliphatic nitrile or an alicyclic nitrile which are separable from water. This reaction may be carried out in the presence of a catalyst such as an N,N-disubstituted amide, a nitrogen-containing heteroaromatic compound, a tertiary amine, etc. COPYRIGHT: (C)2005,JPO&NCIPI
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