The present invention relates generally to therapeutic agents and methods which enhance or otherwise maintain a state of immune tolerance in a subject . The present invention further provides agents and methods for preventing or at least delaying onset of an autoimmune disease such as but not limited to autoimmune diabetes. Furthermore, the agents and methods of the present invention are useful in enhancing the effectiveness of vaccine regimes such as against cancer cells or pathogenic organisms and viruses or for generally enhancing the immune responsiveness against such entities. The present invention further enables the prevention of pathogenic agent-induced autoimmune conditions.
申请公布号
CA2551189(A1)
申请公布日期
2005.07.07
申请号
CA20042551189
申请日期
2004.12.23
申请人
THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH
发明人
FANCKE, BEN;HARRISON, LEN;O'KEEFFE, MEREDITH;STEPTOE, RAY;SHORTMAN, KEN;VREMEC, DAVID