发明名称 BENZYLETHER AND BENZYLAMINO BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE
摘要 The present invention is directed to compounds which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved.
申请公布号 WO2005032471(A3) 申请公布日期 2005.07.07
申请号 WO2004US32009 申请日期 2004.09.29
申请人 MERCK & CO., INC.;NANTERMET, PHILIPPE, G.;RAJAPAKSE, HEMAKA ANTHONY;SELNICK, HAROLD, G. 发明人 NANTERMET, PHILIPPE, G.;RAJAPAKSE, HEMAKA ANTHONY;SELNICK, HAROLD, G.
分类号 A61K;A61K31/195;C07C255/57;C07C311/08;C07D207/06;C07D207/08;C07D213/76;C07D213/81;C07D295/192;C07D333/20;C07D405/04 主分类号 A61K
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