发明名称 ANALYTICAL SANDWICH ASSAY FOR MEASURING NT-PROBNP
摘要 <p><P>PROBLEM TO BE SOLVED: To provide a method for measuring immunologically quickly N-terminal pro-cerebral sodium diuretic peptide (NT-proBNP) that is a marker for diagnosis and control of cardiac failures. <P>SOLUTION: This immunological sandwich method is carried out, using two antibodies against NT-proBNP. One of the antibodies uses a monoclonal antibody (MAB). Two antibodies, capable of recognizing epitopes in two points different in amino acid sequences of the NT-proBNP, are used as the combination of the antibodies. Various kinds of the epitopes are possible. As the method, immunological chromatography is used for the measurement. <P>COPYRIGHT: (C)2005,JPO&NCIPI</p>
申请公布号 JP2005181304(A) 申请公布日期 2005.07.07
申请号 JP20040339760 申请日期 2004.11.25
申请人 F HOFFMANN LA ROCHE AG 发明人 SPINKE JURGEN;NICHTL ALFONS;KLEMT VOLKER;HALLERMAYER KLAUS;GROL MICHAEL;BORGYA ANNELIESE;GALLUSSER ANDREAS
分类号 G01N33/53;G01N33/543;G01N33/577;G01N33/68;G01N33/74;(IPC1-7):G01N33/53 主分类号 G01N33/53
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