发明名称 |
Non-pegylated long-circulating liposomes |
摘要 |
The present invention provides a long circulating non-pegylated liposomal doxorubicin hydrochloride composition for parenteral administration and a process for its preparation. The circulation time in Swiss albino mice is at least 25 times longer than conventional non-liposomal formulations. The non-pegylated liposomes are stable, exhibit low toxicity and have been found to be efficacious in different tumor models. |
申请公布号 |
US2005142178(A1) |
申请公布日期 |
2005.06.30 |
申请号 |
US20030748094 |
申请日期 |
2003.12.31 |
申请人 |
BHARATS SERUMS & VACCINES LTD. |
发明人 |
DAFTARY GAUTAM V.;PAI SRIKANTH A.;RIVANKAR SANGEETA H. |
分类号 |
A61K9/127;A61K31/704;(IPC1-7):A61K9/127 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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