发明名称 |
Catechol bioisosteres |
摘要 |
The present invention provides catechol bioisostere compounds which are potent inhibitors of protein tyrosine kinases (PTKs). The present invention further provides methods of inhibiting PTKs, for example receptor protein tyrosine kinases (RTKs), comprising administering the catechol bioisosteres. The catechol bioisostere compounds are useful in treating or preventing PTK-related disease states, particularly protein tyrosine kinase related disorders which are associated with defects in signaling pathways mediated by PTKs.
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申请公布号 |
US2005143430(A1) |
申请公布日期 |
2005.06.30 |
申请号 |
US20040914010 |
申请日期 |
2004.08.05 |
申请人 |
GAZIT AVIV;LEVITZKI ALEXANDER;BLUM GALIA |
发明人 |
GAZIT AVIV;LEVITZKI ALEXANDER;BLUM GALIA |
分类号 |
A61K31/4184;A61K31/423;A61K31/424;A61P3/00;A61P3/10;A61P5/00;A61P5/50;A61P9/00;A61P9/10;A61P13/12;A61P17/02;A61P17/06;A61P19/04;A61P25/00;A61P27/02;A61P29/00;A61P35/00;A61P43/00;C07D235/24;C07D263/58;(IPC1-7):C07D263/58;A61K31/418 |
主分类号 |
A61K31/4184 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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