一个人类锌指蛋白家族新基因ZNF325

摘要

一个人类锌指蛋白家族新基因ZNF325，涉及一种人类基因，它的cDNA全长2697bp，位于染色体7p22，编码的蛋白质全长462个氨基酸，含15个C²H²型的锌指；ZNF325在成人和胚胎时期广泛表达，说明该基因对人类早期胚胎正常发育和对人体各组织的正常功能起重要作用。

主权项

1、一个人类锌指蛋白家族基因ZNF325，其特征在于该基因的cDNA核苷酸序列如下：accaggtctg gtctacagtc gactaagtcg gtcggcccgg gcccctctgg agcanaangg 60ccttggtgag gcggacagga agggacctcg cgagcagacg cgcgcccgcg acagcaatcc 120cgccccggcc tgtcgggagc ggtggggcag aggctgcgga gccccaggag gatctgcctc 180cgctttcaca gtcctccaga tttttccaag agcagcagaa aatgaataaa tccctggggc 240cagtgtcatt caaggacgtg gctgtggact tcacccagga ggaatggcag cagctggatc 300ctgagcagaa gataacttac agggatgtga tgctggagaa ctacagcaat ctagtttctg 360tggggtatca cattatcaaa ccggatgtta tcagcaagtt ggagcaagga gaagagccat 420ggatagtaga aggagaattc ctacttcaga gctatccaga tgaagtctgg caaactgatg 480acctaataga gagaatccag gaagaggaaa ataaaccttc aaggcaaact gtgttcattg 540agaccctgat tgaagagaga ggtaatgttc ctggtaaaac ttttgatgta gaaacgaacc 600ctgttccttc aagaaaaata gcctataaaa atagcctctg tgactcatgt gaaaagtgtt 660taacgtctgt ttcagaatat attagtagtg atggaagcta tgcaagaatg aaagctgatg 720aatgtagtgg attgtgggaa atcactcctc catattaagc ttgagaaaac tcatccagga 780gatcnagctt atgatttaat caaaatgggg aaccttatac cctaaattga anaagtntta 840tcaaaaattc gtattttgga gaaacctttt gaatatattg aatgccagaa agccttccaa 900aaggacactg tttttgttaa tcacatggaa gaaaagccct ataagtggaa tggatctgaa 960atagcctttc tccagatgtc ggacctcact gtacatcaga catctcatat ggaaatgaag 1020ccctatgaat gcagtgaatg tgggaaatcc ttctgtaaaa agtcaaaatt tattatacat 1080cagaggactc acacaggaga gaaaccttac gaatgtaatc agtgtgggaa atccttctgc 1140cagaagggaa cccttactgt gcatcagaga acacacacag gggagaagcc ctatgaatgt 1200aatgaatgtg ggaagaactt ttaccagaag ttacacctca ttcagcatca gagaactcac 1260tcaggagaga agccctatga atgtagttat tgtggaaaat ccttttgcca gaagacacac 1320ctcacacaac atcagagaac acattcagga gagagacctt atgtttgtca tgactgtggg 1380aaaaccttct cgcagaagtc agcacttaat gaccatcaga aaattcacac aggtgtgaaa 1440ctctacaagt gtagtgaatg tgggaaatgc ttctgccgca agtctactct cacgacccac 1500ctgaggaccc acacaggaga gaaaccgtat gaatgtaatg agtgtggaaa attcttctct 1560cggttgtcat atctcactgt acattataga actcattcag gagagaaacc ctatgaatgt 1620aatgaatgtg gaaaaacctt ctacctgaat tcagccctca tgagacatca gagagtgcac 1680acaggagaga aaccttacga atgtaatgaa tgtggaaagt tattctccca gttgtcatac 1740ctcactatcc atcatagaac tcattcagga gtaaaaccct atgaatgtag tgaatgtggg 1800aaaaccttct accagaactc agccctttgt agacatcgga gaatacacaa aggagagaag 1860ccctatgaat gctatatatg tggaaaattc ttctctcaga tgtcatacct cactatacat 1920catagaattc attcaggaga gaagccctat gaatgtagtg aatgtgggaa aaccttctgc 1980cagaattcag cccttaatcg acatcagaga acacacacag gagagaaagc ctacgaatgt 2040tatgaatgtg ggaagtgctt ctctcagatg tcctatctca ctatacatca tcgaattcat 2100tcaggagaga aaccctttga atgtaatgag tgtggaaaag ccttctctcg gatgtcatac 2160ctcactgtac attatagaac tcattcagga gagaaaccct atgagtgtac tgaatgtgga 2220aaaaaattct accacaaatc agcattcaac agccatcaga gaattcatag gagaggcaat 2280atgaatgtaa tagatgtggg aaggcttctc tgaagtcaga cctcatttta tatcagagaa 2340ccctttcagt atagtgaatc agaaactcct gcctgaagtc aaacaccttg tacatcagag 2400agttcacaca ggttagtgtg gacatcccct tgtgtgttgg actcataatc tgaagactca 2461cagaatggaa accatgatta taacaagacc acatggtata acaatactag actatagaca 2520agtaaaaatt tataaatatt aagaatgtat atacatgtca ccatggattg gaactgtttt 2580gcatatcagg gaaatcatag ccaaggggaa atctatcagt ataaggaatg tggaagacat 2640aatcctttgg aaactgttaa tactaaaaga tatgtttctg atacaatagc aaacttg 2697