摘要 |
There is provided an in vitro method for detecting a viral infection in a sample, wherein the viral infection is selected from the group consisting of: (i) a Hepatitis C viral infection; and (ii) a Hepatitis B viral infection; wherein said method comprises: detecting the level of expression of a polypeptide in the sample, wherein said polypeptide comprises a sequence of amino acid residues that is at least 90% identical to: (i) amino acids 21-223 of SEQ ID NO: 2; (ii) amino acids 21-226 of SEQ ID NO: 2; (iii) amino acids 21-223 of SEQ ID NO: 19; or (iv) amino acids 21-226 of SEQ ID NO: 19; or wherein the polypeptide consists of a sequence of amino acid residues that is at least 90% identical to: (v) amino acids 1-491 of SEQ ID NO: 2; (vi) amino acids 1-520 of SEQ ID NO: 19; or (vii) amino acids 1- 211 of SEQ ID NO: 21; and detecting expression of said polypeptide in a control; and comparing the level of expression of the polypeptide in the sample to the level of the polypeptide in the control; and wherein the level of expression of the polypeptide in the sample is greater than the level of polypeptide in the control. |