发明名称 Methods of treatment using thiazoline acid derivatives
摘要 Disclosed is a method of treating a pathological condition in a non-human mammal associated with an excess of a trivalent metal, ion of compound there of comprising administering to the animal a compound of the formulas I-VI, wherein: R may be H or acyl; R1, R2, R3, R4 and R7 may be the same or different and represent H, alkyl or hydrocarbyl arylalkyl having up to 14 carbon atoms, or ûCH2-[O-(Ch2)x]y-OCH3, wherein x is 1-10 and y is 0-10; R5 is H, alkyl having up to 15 carbon atoms, ûCH2)1-2-[O-(Ch2)x]y-OCH3, wherein x is 1-10 and y is 0-10, or ûCH2-NOH-CO-[(Ch2)z-NOH-CO]q-R1, wherein R1 is as defined above, z is 1-10 and q is 0-5; R6 is H or acyl; n is 0-10; or a salt thereof with a pharmaceutically acceptable acid or a pharmaceutically acceptable complex thereof. (62) Divided out of 332049
申请公布号 NZ509967(A) 申请公布日期 2005.06.24
申请号 NZ19970509967 申请日期 1997.03.31
申请人 UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC 发明人 BERGERON, RAYMOND J
分类号 A61K31/425;A61K31/426;A61P43/00;C07D277/10;C07D277/12;C07D417/04;(IPC1-7):A61K31/425 主分类号 A61K31/425
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