| 摘要 |
One or more cardiovascular parameters is estimated as a function of the arterial pressure waveform (P(t)), in particular, using at least one statistical moment (µ2P, µ3P, and µ4P) of a discrete representation (P(k)) pressure waveform having an order greater than one. Arterial pressure may be measured invasively or non-invasively. Arterial compliance (K), an exponential pressure decay constant (tau), vascular resistance (R), cardiac output (CO), and stroke volume (SV) are examples of cardiovascular parameters that can be estimated using various aspects of the invention. In a single-moment embodiment of the invention, cardiac stroke volume (SV) of a subject is estimated as a function of a value derived from the pressure waveform. In a multi-moment embodiment of the invention, two or more of the first four moments - mean, standard deviation, skewness, and kurtosis - of the pressure waveform are used to estimate the cardiovascular parameter(s) of interest, as well as heart rate, statistical moments (µ1T, µ2T, µ3T, µ4T) of a set of pressure-weighted time values (T(j)), and certain anthropometric patient measurements such as age, sex, body surface area, etc. |
