Use of modulators of aquaglyceroporins as slimming agents

摘要

Adipose aquaglyceroporin (AQPap) modulators that stimulate the AQPap activity of adipocytes are used in cosmetic compositions as slimming agents for reducing the volume of adipocytes, are new. Independent claims are also included for: (1) cosmetic composition comprising an adipose aquaglyceroporin modulator as above and a lipolytic agent; (2) use of escin, proanthocyanidins, diosgenin and ginkgo extracts for modulating the aquaglyceroporins of adipose tissue. ACTIVITY : Anorectic. No biological data given. MECHANISM OF ACTION : Adipose aquaglyceroporin modulator; phosphodiesterase inhibitor; alpha -2 receptor inhibitors, neuropeptide Y inhibitors, LDL or VLDL receptor synthesis inhibitors, beta receptor activators, G-protein activators, glucose transport blockers, adenylcyclase activator. No biological data given.