| 发明名称 |
Antimicrobial cationic peptides |
| 摘要 |
A novel class of cationic peptides having antimicrobial activity is provided. Examples of such peptides include NH<SUB>2</SUB>-KWKSFIKKLTTAVKKVLTTGLPALIS-COOH (SEQ ID NO:1) and NH<SUB>2</SUB>-KWKSFIKKLTSAAKKVVTTAKPLISS-COOH (SEQ ID NO:2). Also provided are methods for inhibiting the growth of bacteria utilizing the peptides of the invention. The peptides are particularly useful for inhibiting endotoxemia in a subject.
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| 申请公布号 |
US6906035(B2) |
申请公布日期 |
2005.06.14 |
| 申请号 |
US20020272248 |
申请日期 |
2002.10.15 |
| 申请人 |
THE UNIVERSITY OF BRITISH COLUMBIA |
发明人 |
HANCOCK ROBERT E. W.;KARUNARATNE NEDRA |
| 分类号 |
A61K38/00;A61K38/16;C07K7/08;C07K14/00;C07K14/435;(IPC1-7):A61K38/00;A61K49/00 |
主分类号 |
A61K38/00 |
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