发明名称 |
Combination of cytochome p450 dependent protease inhibitors |
摘要 |
The present invention relates to a method for improving the pharmacokinetics of hexahydrofuro[2,3-b]furanyl containing HIV protease inhibitors comprising administering to a human in need thereof a combination of a therapeutically effective amount of a hexahydrofuro[2,3-b]furanyl containing HIV protease inhibitor, and a therapeutically effective amount of a cytochrome P<SUB>450 </SUB>inhibitor.
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申请公布号 |
US2005119338(A1) |
申请公布日期 |
2005.06.02 |
申请号 |
US20040498024 |
申请日期 |
2004.11.16 |
申请人 |
VAN DER GEEST RONALD;STOFFELS PAUL;GROEN CORNELIS;DIRK EDWARD DESIRE JOCHMANS |
发明人 |
VAN DER GEEST RONALD;STOFFELS PAUL;GROEN CORNELIS;DIRK EDWARD DESIRE JOCHMANS |
分类号 |
C07D493/04;A61K31/34;A61K31/365;A61K31/4164;A61K31/427;A61K31/496;A61K31/635;A61K45/00;A61P31/12;A61P31/18;A61P43/00;(IPC1-7):A61K31/343 |
主分类号 |
C07D493/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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