发明名称 Combination of cytochome p450 dependent protease inhibitors
摘要 The present invention relates to a method for improving the pharmacokinetics of hexahydrofuro[2,3-b]furanyl containing HIV protease inhibitors comprising administering to a human in need thereof a combination of a therapeutically effective amount of a hexahydrofuro[2,3-b]furanyl containing HIV protease inhibitor, and a therapeutically effective amount of a cytochrome P<SUB>450 </SUB>inhibitor.
申请公布号 US2005119338(A1) 申请公布日期 2005.06.02
申请号 US20040498024 申请日期 2004.11.16
申请人 VAN DER GEEST RONALD;STOFFELS PAUL;GROEN CORNELIS;DIRK EDWARD DESIRE JOCHMANS 发明人 VAN DER GEEST RONALD;STOFFELS PAUL;GROEN CORNELIS;DIRK EDWARD DESIRE JOCHMANS
分类号 C07D493/04;A61K31/34;A61K31/365;A61K31/4164;A61K31/427;A61K31/496;A61K31/635;A61K45/00;A61P31/12;A61P31/18;A61P43/00;(IPC1-7):A61K31/343 主分类号 C07D493/04
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