DNA VACCINES ENCODING HSP60 PEPTIDE FRAGMENTS FOR TREATING AUTOIMMUNE DISEASES
摘要
The present invention is related to recombinant constructs encoding active fragments of HSP60 which are effective in treating T cell-mediated inflammatory autoimmune diseases by DNA vaccines. The HSP60 fragments of the present invention are identified by their ability to react with T cells isolated from an animal vaccinated with DNA constructs encoding HSP70 to induce Th2/3 T-cell responses.
申请公布号
WO2005048914(A2)
申请公布日期
2005.06.02
申请号
WO2004IL01080
申请日期
2004.11.24
申请人
YEDA RESEARCH & DEVELOPMENT CO. LTD.;COHEN, IRUN, R.;QUINTANA, FRANCISCO