发明名称 |
Method for detecting environmental pollution using 14-3-3 proteins as biomarkers. |
摘要 |
<p>Method for monitoring natural and anthropogenic environmental chemicals in water or soil comprises assaying for protein 14-3-3 (Trends Biochem. Sci., 17, 498, 1992) as a biomarker in vertebrate or invertebrate indicator organisms exposed to the water or soil. An independent claim is also included for an enzyme-linked immunosorbent assay (ELISA) for determining the presence and amount of protein 14-3-3 in an extract or body fluid sample, comprising: (1) introducing the sample into a microtiter plate well coated with a 14-3-3-binding peptide, either directly or by interaction of the biotinylated peptide with a streptavidin coating, and (2) detecting and quantifying complex formation. ACTIVITY : None given. MECHANISM OF ACTION : None given.</p> |
申请公布号 |
EP1536235(A2) |
申请公布日期 |
2005.06.01 |
申请号 |
EP20040029992 |
申请日期 |
1999.03.10 |
申请人 |
MUELLER, WERNER E. G.;SCHROEDER, HEINZ C. |
发明人 |
MUELLER, WERNER E. G.;SCHROEDER, HEINZ C. |
分类号 |
G01N33/50;G01N33/68;(IPC1-7):G01N33/68 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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