发明名称 NOVEL 3-ARYL-2,5-DIHYDROXY-1,4-BENZOQUINONE DERIVATIVES, THEIR PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME
摘要 Compound of formula (I): wherein: R<SUB>1 </SUB>and R<SUB>2</SUB>, which may be identical or different, each represents hydrogen, acyl or alkyl, Ar represents aryl or heteroaryl, A represents a group selected from: R<SUB>4 </SUB>represents hydrogen or alkyl, R<SUB>5 </SUB>represents hydrogen, alkyl, aryl or heteroaryl, R<SUB>3 </SUB>represents aryl, heteroaryl, dicyclopropylmethyl or benzhydryl, or A-R<SUB>3 </SUB>represents an optionally substituted naphthyl group, with the exclusion of 2,5-dihydroxy-3-(4-methoxyphenyl)-6-(2-phenylethenyl)-1,4-benzoquinone, 2,5-dihydroxy-3-(4-methoxyphenyl)-6-(2-naphthyl)-1,4-benzoquinone and 2,5-dihydroxy-3-(2-naphthyl)-6-phenyl-1,4-benzoquinone. Medicinal products containing the same which are useful in the treatment of diseases associated with a deregulation of glycaemia.
申请公布号 PL370773(A1) 申请公布日期 2005.05.30
申请号 PL20030370773 申请日期 2003.02.04
申请人 LES LABORATOIRES SERVIER 发明人 DASSONVILLE ALEXANDRA;BRETECHE ANNE;DUFLOS MURIEL;LE BAUT GUILLAUME;PFEIFFER BRUNO;RENARD PIERRE;LEVENS NIGEL;HUSSON-ROBERT BERNADETTE
分类号 A61K31/122;A61K31/222;A61K31/4402;A61P3/10;C07C45/00;C07C45/28;C07C46/00;C07C46/10;C07C50/28;C07C50/30;C07D213/50 主分类号 A61K31/122
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