NUCLEIC ACID DETECTION METHOD HAVING INCREASED SENSITIVITY
摘要
The present disclosure relates to methods of detecting nucleic acid hybridization by monitoring an output signal. Some advantageous embodiments include techniques which can augment the signal. One such technique involves catalytic detection, such as with a peroxidase or other enzyme. Another technique involves "on-chip" amplification to enlarge the nucleic acid after hybridization has occurred.
申请公布号
WO2005047474(A2)
申请公布日期
2005.05.26
申请号
WO2004US37407
申请日期
2004.11.10
申请人
GENEOHM SCIENCES, INC.;CROTHERS, DONALD, M.;HOLMLIN, R., ERIK;ZHANG, HONGHUA;SHI, CHUNNIAN
发明人
CROTHERS, DONALD, M.;HOLMLIN, R., ERIK;ZHANG, HONGHUA;SHI, CHUNNIAN