发明名称 |
DIAGNOSTIC ASSAY AND METHOD OF TREATMENT INVOLVING MACROPHAGE INHIBITORY CYTOKINE -1 (MIC-1) |
摘要 |
Methods for diagnosing risk of miscarriage and/or premature birth, foetal abnormalities, cancer (e.g. prostate cancer) and inflammatory disease (e.g. rheumatoid arthritis) are disclosed which involve determining abnormal levels of macrophage inhibitory cytokine-1 (MIC-1) in a body sample or, otherwise, determining the presence of a MIC-1 variant protein. Also disclosed are methods for reducing the risk of miscarriage and/or premature birth in pregnant subjects, and methods for treatment of inflammatory disease and/or cancer. |
申请公布号 |
EP1279039(A4) |
申请公布日期 |
2005.05.25 |
申请号 |
EP20010923411 |
申请日期 |
2001.04.20 |
申请人 |
ST VINCENT'S HOSPITAL SYDNEY LIMITED |
发明人 |
BREIT, SAMUEL, NORBERT;BROWN, DAVID ALEXANDER |
分类号 |
G01N33/53;A61K38/00;A61K38/19;A61K48/00;A61P15/06;A61P29/00;A61P35/00;A61P43/00;C07K16/24;C12N15/09;C12N15/19;C12Q1/68;G01N33/574;G01N33/68;(IPC1-7):G01N33/68 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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