发明名称 |
Guanylate binding protein (GBP-1) as inhibitor of cell proliferation and molecular marker for the determination of the stage of cellular differentiation |
摘要 |
The present invention relates to an expression vector comprising the Guanylate Binding Protein 1 (GBP-1) gene or parts thereof. The introduction of said vector comprising said gene or parts thereof in sense or antisense orientation into cells can be used to induce phenotypical changes of said cells and can, thus, be used for modulation of cell differentiation. Additionally, the present invention provides, inter alia, a method for determination of the stage of cellular differention by using GBP-1 gene expression as a marker.
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申请公布号 |
US6894157(B2) |
申请公布日期 |
2005.05.17 |
申请号 |
US20010791502 |
申请日期 |
2001.02.23 |
申请人 |
STUERZL MICHAEL;CORNALI EMMANUELLE |
发明人 |
STUERZL MICHAEL;CORNALI EMMANUELLE |
分类号 |
G01N33/53;A61K31/7105;A61K31/711;A61K38/00;A61K39/00;A61K39/395;A61K39/42;A61K45/00;A61K48/00;A61P17/00;A61P29/00;A61P35/00;A61P37/02;C07K14/16;C07K14/47;C07K16/18;C07K19/00;C12N5/10;C12N7/00;C12N15/09;C12N15/12;C12P21/02;C12P21/08;C12Q1/02;C12Q1/68;G01N33/566;(IPC1-7):C07H21/04;C12P21/06;C12N15/74;C12N5/02;C07K14/00 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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