METHOD OF COMPLEXING A NUCLEIC ACID WITH A LIPID-CONJUGATED POLYAMIDE

摘要

In accordance with the present invention, there are provided lipid-conjugated polyamide compounds and related compositions and methods thereof Lipid-conjugated polyamide compounds of the present invention are particularly useful as vehicles for delivering biologically active agents to a target site. In particular, the invention compounds are effective at facilitating the delivery of polynucleotides to cells. The present invention also provides a method for producing stable formulations of polynucleotides complexed with a delivery vehicle.