| 摘要 |
The invention comprises steroids of the formulae <FORM:1029919/C2/1> (wherein R1 is H or C1-5 alkyl, R2 is a C1-5 aliphatic hydrocarbon group and R3 is H or Me) and acid-addition salts thereof. They may be prepared by reacting the corresponding 2-hydroxymethyl-3-keto-androstanes with hydrazines R1NHNH2. Products wherein R1 is hydrogen may be N-alkylated to give a mixture of isomers of the above general formulae. Examples are given. The steroids of the invention are anabolics and they may be made up into pharmaceutical or veterinary compositions with suitable carriers. These may take the form of tablets, dragees, ointments, creams, solutions, suspensions or emulsions and may contain preservers, stabilizers, wetting agents, emulsifiers, salts for regulating the osmotic pressure or buffers. |
