发明名称 |
BIOMARKERS FOR AMYOTROPHIC LATERAL SCLEROSIS |
摘要 |
The invention provides a method for diagnosing amyotrophic lateral sclerosis (ALS) in a subject, a method for assessing the effectiveness of a drug in treating ALS, and a method for determining the site of onset of ALS in a subject. Each method comprises (a) obtaining a sample from the subject, (b) analyzing the proteins in the sample by mass spectroscopy, and (c) determini ng a mass spectral profile for the sample. In some embodiments, the method comprises comparing the mass spectral profile of the sample to the mass spectral profile of a positive or a negative standard. |
申请公布号 |
CA2542391(A1) |
申请公布日期 |
2005.05.12 |
申请号 |
CA20042542391 |
申请日期 |
2004.10.25 |
申请人 |
UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION</SNM |
发明人 |
RANGANATHAN, SRIKANTH;BOWSER, ROBERT P. |
分类号 |
G01N33/487;C12Q;G01N33/00;G01N33/483;G01N33/53;G01N33/68 |
主分类号 |
G01N33/487 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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